This could be an issue with a corrupt hibernation file.
Watch for errors as Mac boots, and google any errors found. Can sometimes fix a desktop Mac that won't boot.
To leave safe mode, restart your Mac without pressing any keys during startup. If your startup disk is encrypted with FileVault, you might be asked to log in twice: once to unlock the startup disk, and again to log in to the Finder. Release the shift key when you see the login window. If you don't see the Apple logo, learn what to do. The white Apple logo appears on your display.
Mac laptops usually have a colored indicator where the AC adapter connects to the laptop, this is green when the computer is on, or when the battery is fully charged, or orange when the battery is charging. Notice that the "Open" dot or arrow disappears, indicating that the application has been closed.